1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol
- CasNo:93413-76-4
Product Description
Quality products?make an important contribution to long-term revenue and profitability. 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol Good Manufacturer supply High Quality 93413-76-4
1.What is the 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol ?
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108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone
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![1-[cyano(4-methoxyphenyl)methyl]cyclohexanol](/upload/2026/10/0c3021d577dd4d559493e6a3c8d6546e_85cc4378-e613-4f9d-b4a4-ed3e370ee210.png)
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93413-76-4,131801-69-9
1-[cyano(4-methoxyphenyl)methyl]cyclohexanol
| Conditions | Yield |
|---|---|
|
p-methoxybenzylnitrile;
With
sodium hydroxide;
polyethylene glycol;
In
water;
at 0 - 5 ℃;
for 2h;
cyclohexanone;
With
sodium hydroxide;
In
water;
at 0 - 20 ℃;
for 13.5h;
|
90%
|
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108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone
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104-47-2
p-methoxybenzylnitrile
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93413-76-4,131801-69-9
1-[cyano(4-methoxyphenyl)methyl]cyclohexanol
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate;
In
methanol;
at 25 - 30 ℃;
for 6h;
|
98%
|
|
With
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate;
at 0 - 15 ℃;
for 1h;
|
97%
|
|
With
sodium hydroxide;
tetra(n-butyl)ammonium hydrogensulfate;
In
water;
at 0 - 15 ℃;
for 2.2h;
|
97.6%
|
|
With
tetrabutylammomium bromide; sodium methylate;
at 25 - 30 ℃;
for 15h;
|
96%
|
|
With
tetrabutylammomium bromide; water; sodium hydroxide;
In
methanol;
at 20 ℃;
for 15h;
|
96%
|
|
With
ion-exchange resin IRA-900 (OH);
at -60 ℃;
for 100h;
Flow reactor;
|
94%
|
|
With
tetrabutylammomium bromide; sodium hydroxide;
In
toluene;
at 50 ℃;
for 5h;
Reagent/catalyst;
Solvent;
|
93.7%
|
|
p-methoxybenzylnitrile;
With
sodium methylate;
In
methanol;
at 0 - 5 ℃;
for 2h;
Large scale reaction;
cyclohexanone;
In
methanol;
at 0 - 5 ℃;
for 4h;
Large scale reaction;
|
91%
|
|
With
tetrabutylammomium bromide; sodium hydroxide;
In
methanol; water;
for 3h;
|
91.3%
|
|
With
1,8-diazabicyclo[5.4.0]undec-7-ene; potassium hydroxide;
In
methanol; water;
at 15 - 20 ℃;
for 24h;
|
90%
|
|
tetra-(n-butyl)ammonium iodide;
In
water;
at 0 ℃;
for 0.166667h;
|
89.7%
|
|
p-methoxybenzylnitrile;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -75 - -70 ℃;
for 0.5h;
cyclohexanone;
In
tetrahydrofuran; hexane;
at -70 - -65 ℃;
for 4h;
With
water; ammonium chloride;
In
tetrahydrofuran; hexane;
at 0 ℃;
|
89%
|
|
potassium tert-butylate;
In
n-heptane;
at 20 ℃;
for 0.833333h;
Product distribution / selectivity;
|
88.8%
|
|
cyclohexanone; p-methoxybenzylnitrile;
potassium tert-butylate;
In
n-heptane;
at 20 ℃;
for 0.833333h;
With
acetic acid;
In
n-heptane;
Product distribution / selectivity;
|
88.8%
|
|
With
sodium methylate;
In
methanol;
at -5 - -2 ℃;
|
86.75%
|
|
p-methoxybenzylnitrile;
With
sodium methylate;
In
methanol;
at 0 - 5 ℃;
for 1.25 - 1.5h;
cyclohexanone;
In
methanol;
at 0 - 5 ℃;
for 3.5 - 4.16667h;
Product distribution / selectivity;
|
85%
|
|
potassium tert-butylate;
at 20 - 25 ℃;
for 0.5h;
Product distribution / selectivity;
|
82.4%
|
|
cyclohexanone; p-methoxybenzylnitrile;
potassium tert-butylate;
at 20 - 25 ℃;
for 0.5h;
With
acetic acid;
In
n-heptane;
at 10 ℃;
for 0.5h;
pH=3 - 4;
Product distribution / selectivity;
|
82.4%
|
|
p-methoxybenzylnitrile;
With
sodium methylate;
In
methanol;
at -5 - -3 ℃;
for 2h;
cyclohexanone;
In
methanol;
at -5 - -3 ℃;
for 10 - 12h;
With
water;
at 0 - 2 ℃;
for 0.5h;
|
80%
|
|
p-methoxybenzylnitrile;
With
lithium diisopropyl amide;
In
tetrahydrofuran;
at -78 - -65 ℃;
for 0.5h;
cyclohexanone;
In
tetrahydrofuran;
at -78 - -65 ℃;
for 2h;
|
80.7%
|
|
p-methoxybenzylnitrile;
With
lithium diisopropyl amide;
In
tetrahydrofuran;
at -78 - -65 ℃;
for 0.5h;
cyclohexanone;
In
tetrahydrofuran;
at -78 - -65 ℃;
for 2h;
|
80.7%
|
|
p-methoxybenzylnitrile;
With
lithium diisopropyl amide;
In
tetrahydrofuran;
at -78 - -65 ℃;
for 0.5h;
cyclohexanone;
In
tetrahydrofuran;
at -78 - -62 ℃;
for 2h;
With
water; ammonium chloride;
In
tetrahydrofuran;
at 0 ℃;
for 0.25h;
|
80.7%
|
|
With
sodium hydroxide;
In
water;
at 0 ℃;
for 0.166667h;
|
78%
|
|
tetra(n-butyl)ammonium hydroxide;
at 20 - 25 ℃;
for 0.25h;
Product distribution / selectivity;
|
73.6%
|
|
cyclohexanone; p-methoxybenzylnitrile;
tetra(n-butyl)ammonium hydroxide;
In
water;
at 20 - 25 ℃;
for 0.25h;
With
hydrogenchloride;
In
water; toluene;
at 30 ℃;
Product distribution / selectivity;
|
73.6%
|
|
potassium tert-butylate;
In
toluene;
at 20 - 26 ℃;
for 24h;
Product distribution / selectivity;
|
68.2%
|
|
cyclohexanone; p-methoxybenzylnitrile;
potassium tert-butylate;
In
toluene;
at 20 - 26 ℃;
for 24h;
With
acetic acid;
In
n-heptane;
at 10 ℃;
for 0.5h;
pH=3 - 4;
Product distribution / selectivity;
|
68.2%
|
|
With
n-butyllithium;
Yield given. Multistep reaction;
1.) THF, hexane, -70 deg C, 30 min, 2.) -65 deg C, 2 h;
|
|
|
With
sodium hydroxide; polyethyleneglycol monomethylether;
In
water;
at 20 ℃;
for 7 - 8h;
Product distribution / selectivity;
|
|
|
With
potassium hydroxide; polyethyleneglycol monomethylether;
In
water;
at 5 - 25 ℃;
for 5h;
Product distribution / selectivity;
|
|
|
With
potassium hydroxide;
In
polyethyleneglycol monomethyl ether; water;
at 5 - 25 ℃;
for 5h;
Product distribution / selectivity;
|
|
|
With
sodium hydroxide;
In
ethanol; water;
at 25 ℃;
for 4h;
Product distribution / selectivity;
|
|
|
With
sodium hydroxide;
In
ethanol; water;
at 25 ℃;
for 4h;
Product distribution / selectivity;
|
|
|
With
sodium hydroxide;
In
polyethyleneglycol monomethyl ether; water;
at 20 ℃;
for 7 - 8h;
Product distribution / selectivity;
|
|
|
With
sodium hydroxide;
tetrabutylammomium bromide;
In
water;
at 15 - 18 ℃;
for 1.75h;
|
|
|
With
sodium butanolate;
In
butan-1-ol;
at -10 - -5 ℃;
for 2.66667 - 2.83333h;
Product distribution / selectivity;
|
|
|
With
sodium t-butanolate;
In
tert-butyl alcohol;
at -10 - -5 ℃;
for 2.66667 - 2.83333h;
Product distribution / selectivity;
|
|
|
With
sodium isobutoxide;
In
2-methyl-propan-1-ol;
at -10 - -5 ℃;
for 2.66667 - 2.83333h;
Product distribution / selectivity;
|
|
|
p-methoxybenzylnitrile;
With
hexamethylenetetramine; potassium carbonate;
In
dimethyl sulfoxide;
at 25 - 92 ℃;
for 1 - 1.5h;
cyclohexanone;
In
dimethyl sulfoxide;
at 20 ℃;
for 1.5 - 2h;
|
|
|
p-methoxybenzylnitrile;
With
sodium methylate;
In
methanol;
at -5 - -3 ℃;
Inert atmosphere;
cyclohexanone;
In
methanol;
at -5 - -3 ℃;
With
water;
In
methanol;
at 0 - 2 ℃;
for 0.5h;
|
|
|
With
sodium hydroxide;
In
methanol; water;
|
|
|
With
pyridine;
In
tetrahydrofuran;
at 45 - 65 ℃;
Solvent;
Reagent/catalyst;
Temperature;
|
451.4 g
|
|
In
ethanol;
at 15 - 30 ℃;
Alkaline conditions;
|
2.What is the CAS number for 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol ?
The CAS number of 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol is 93413-76-4.
More information of 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol 93413-76-4 are:
|
CAS?Number |
93413-76-4 |
|
Density |
1.142 g/cm3 |
|
Melting Point |
121-123 °C |
|
Boiling Point |
410.146 °C at 760 mmHg |
|
Flash Point |
201.849 °C |
|
Vapor Pressure |
0mmHg at 25°C |
|
Refractive Index |
1.561 |
|
HS CODE |
2926909090 |
|
PSA |
53.25000 |
|
LogP |
2.99758 |
|
Pka |
13.80±0.20(Predicted) |
3.What are another words for 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol ?
Synonyms?for?1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol 93413-76-4:1-[Cyano(4-methoxyphenyl)methyl]cyclohexanol;
4.What is the molecular formula of 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol?
The chemical formula of ?1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol is?C15H19NO2 which containing 15 Carbon atoms,19 Hydrogen atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol?is 245.321.
5.What is 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol (93413-76-4) used for?
InChI:InChI=1/C15H19NO2/c1-18-13-7-5-12(6-8-13)14(11-16)15(17)9-3-2-4-10-15/h5-8,14,17H,2-4,9-10H2,1H3
Relevant articles related to 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol:
|
Article |
Source |
|
Preparation method of venlafaxine amine impurity |
- Paragraph 0016; 0033-0035, (2021/05/12) |
|
Preparation method of venlafaxine impurity E (by machine translation) |
- Paragraph 0025; 0029, (2020/09/30) |
6.Buy 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol with the best price .
Shanghai Huachu Industrial Co. Ltd is a quality supplier of 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 1-[Cyano-(p-methoxyphenyl)methyl]cyclohexanol 93413-76-4.