EGT1442
- CasNo:1118567-05-7
Product Description
Cosmetics Grade EGT1442 1118567-05-7 For Sale with Good Price We supply high quality EGT1442 (CAS 1118567-05-7), in stock, factory directly supply to clients, lower prices, more competitiveness.
What is the EGT1442 ?
EGT1442 is , while it's Molecular Formula is C24H29ClO7. Bexagliflozin, also known as EGT1442, is a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA(1c) levels in db/db mice and prolongs the survival of stroke-prone rats. EGT1442 showed favorable properties both in vitro and in vivo and could be beneficial to the management of type 2 diabetic patients.
What is the CAS number for EGT1442 ?
The CAS number of EGT1442 is 1118567-05-7.
More information of EGT1442 1118567-05-7 are:
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Synonyms |
EGT1442;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[2-(cyclopropyloxy)ethoxy]phenyl]methyl]phenyl]-D-glucitol;Bexagliflozin |
|
CAS?Number |
1118567-05-7 |
|
Molecular Formula |
C24H29ClO7 |
|
Molecular Weight |
464.943 |
|
Density |
1.41 |
|
Boiling Point |
671.0±55.0 °C(Predicted) |
|
PSA |
108.61000 |
|
LogP |
2.00350 |
|
Pka |
13.23±0.70(Predicted) |
What is EGT1442 (1118567-05-7) used for?
EGT-1442 is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 5.6 μM and 2 nM for human SGLT1 and SGLT2, respectively. It produces a stable urinary excretion of glucose in rats and dogs with ED50 values of 0.38 and 0.09 mg/kg, respectively, and reduces HbA(1c) and blood glucose in db/db mice in a concentration dependent manner.
Articles related to EGT1442:
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Article |
Source |
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An efficient method for synthesis of bexagliflozin and its carbon-13 labeled analogue |
Xu, Ge,Xu, Baihua,Song, Yanli,Sun, Xun supporting information, p. 4684 - 4687 (2016/09/28) |
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PROCESS FOR THE PREPARATION OF BENZYLBENZENE SGLT2 INHIBITORS |
- Paragraph 0206; 0207; 0208; 0209; 0210, (2013/11/05) |
How to get the best price on EGT1442?
Shanghai Huachu Industrial Co. Ltd is a quality supplier and manufacturer of EGT1442 . You can buy high quality, low price EGT1442 1118567-05-7 here. Contact us.